The Beans or Brain?- The ACORN trial and effects of cefepime and pip-tazo on neuro and renal outcomes

In the Emergency Department, we often have to initiate empiric antibiotic treatment for sick, undifferentiated patients. Cefepime and Piperacillin-Tazobactam (pip-tazo) are common antibiotic options for coverage of gram-negative organisms, such as pseudomonas. But is one better than the other? In this podcast, we will critically appraise The ACORN Trial- an article that examines the risks of acute kidney injury and/or neurologic dysfunction in patients treated empirically with one of these antibiotics.  Contributor: Dillon Warr, MD Effect of Antibiotic Choice On […]

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